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Produktbild: Pharmaceutical Biotechnology

Pharmaceutical Biotechnology Concepts and Applications

117,99 €

inkl. gesetzl. MwSt., Versandkostenfrei

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

01.09.2007

Verlag

John Wiley & Sons

Seitenzahl

504

Maße (L/B/H)

24,7/19/3,3 cm

Gewicht

983 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-0-470-01245-1

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

01.09.2007

Verlag

John Wiley & Sons

Seitenzahl

504

Maße (L/B/H)

24,7/19/3,3 cm

Gewicht

983 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-0-470-01245-1

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Pharmaceutical Biotechnology
  • 1 Pharmaceuticals, Biologics and Biopharmaceuticals
     
    1.1 Introduction to pharmaceutical products
     
    1.2 Biopharmaceuticals and pharmaceutical biotechnology
     
    1.3 History of the pharmaceutical industry
     
    1.4 The age of biopharmaceuticals
     
    1.5 Biopharmaceuticals: current status and future prospects
     
    Further reading 2 Protein Structure
     
    2.1 Introduction
     
    2.2 Overview of protein structure
     
    2.3 Higher level structure
     
    2.4 Protein stability and folding
     
    2.5 Protein post-translational modification
     
    Further reading 3 Gene Manipulation and Recombinant DNA Technology
     
    3.1 Introduction
     
    3.2 Nucleic acids: function and structure
     
    3.3 Recombinant production of therapeutic proteins
     
    3.4 Classical gene cloning and identification
     
    Further reading 4 The Drug Development Process
     
    4.1 Introduction
     
    4.2 Discovery of biopharmaceuticals
     
    4.3 The impact of genomics and related technologies upon drug discovery
     
    4.4 Gene chips
     
    4.5 Proteomics
     
    4.6 Structural genomics
     
    4.7 Pharmacogenetics
     
    4.8 Initial product characterization
     
    4.9 Patenting
     
    4.10 Delivery of biopharmaceuticals
     
    4.11 Preclinical studies
     
    4.12 Pharmacokinetics and pharmacodynamics
     
    4.13 Toxicity studies
     
    4.14 The role and remit of regulatory authorities
     
    4.14 Conclusion
     
    Further reading 5 Sources and Upstream Processing
     
    5.1 Introduction
     
    5.2 Sources of biopharmaceuticals
     
    5.3 Upstream processing
     
    Further reading 6 Downstream Processing
     
    6.1 Introduction
     
    6.2 Initial product recovery
     
    6.3 Cell disruption
     
    6.4 Removal of nucleic acid
     
    6.5 Initial product concentration
     
    6.6 Chromatographic purification
     
    6.7 High-performance liquid chromatography of proteins
     
    6.8 Purification of recombinant proteins
     
    6.9 Final product formulation
     
    Further reading 7 Product Analysis
     
    7.1 Introduction
     
    7.2 Protein-based contaminants
     
    7.3 Removal of altered forms of the protein of interest from the product stream
     
    7.4 Detection of protein-based product impurities
     
    7.5 Immunological approaches to detection of contaminants
     
    7.6 Endotoxin and other pyrogenic contaminants
     
    Further reading 8 The Cytokines: The Interferon Family
     
    8.1 Cytokines
     
    8.2 The interferons
     
    8.3 Interferon biotechnology
     
    8.4 Conclusion
     
    Further reading 9 Cytokines: Interleukins and Tumour Necrosis Factor
     
    9.1 Introduction
     
    9.2 Interleukin-2
     
    9.3 Interleukin-1
     
    9.4 Interleukin-11
     
    9.5 Tumour necrosis factors
     
    Further reading 10 Growth Factors
     
    10.1 Introduction
     
    10.2 Haematopoietic growth factors
     
    10.3 Growth factors and wound healing
     
    Further reading 11 Therapeutic Hormones
     
    11.1 Introduction
     
    11.2 Insulin
     
    11.3 Glucagon
     
    11.4 Human growth hormone
     
    11.5 The gonadotrophins
     
    11.6 Medical and veterinary applications of gonadotrophins
     
    11.7 Additional recombinant hormones now approved
     
    11.8 Conclusion
     
    Further reading 12 Recombinant Blood Products and Therapeutic Enzymes
     
    12.1 Introduction
     
    12.2 Haemostasis
     
    12.3 Anticoagulants
     
    12.4 Thrombolytic agents
     
    12.5 Enzymes of therapeutic value
     
    Further reading 13 Antibodies, Vaccines and Adjuvants
     
    13.1 I