Cell Motility From Molecules to Organisms
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Sprache:Englisch
245,99 €
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Produktdetails
Format
Kopierschutz
Ja
Family Sharing
Nein
Text-to-Speech
Nein
Erscheinungsdatum
11.04.2005
Herausgeber
Anne Ridley + weitereVerlag
WileySeitenzahl
364 (Printausgabe)
Dateigröße
4767 KB
Auflage
1. Auflage
Sprache
Englisch
EAN
9780470094099
Recent advances in molecular and biophysical techniques,
particularly fluorescence and live cell imaging, are
revolutionizing the study of cell motility. New bioprobes not only
reveal simple intracellular localization, but also contain details
of post-translational modifications, conformational state and
protein-protein interactions. Coupling these insights with
complementary advances in genetic and biochemical methods is
enabling scientists to understand the processes involved in cell
motility - from molecular motors to cell movements in vivo in a
range of organisms and cell types.
This book features landmark essays that provide an up to date and
fascinating account of current research and concepts in cell
motility.These cover the roles of molecular motors that drive
movement and their interactions with the cytoskeleton as well as
membrane dynamics that allow cells to change shape and to
move.
Cell motility plays a key role in development - there are chapters
on the genetics of cell migration, the regulation of contact
repulsion in growth cones, and the progression from cell migration
to cell-cell adhesion. Cell motility is directional - experts
describe the molecules that regulate chemotaxis, allowing cells to
migrate along pathways specified by chemical gradients. Finally,
cell motility can be perturbed by mutation--metastasis occurs when
cells lose their normal intercellular interactions and invade other
tissue types. All these processes are regulated by signals from the
environment, including other tissues in the body, and the various
molecules that transmit and transduce these signals are
discussed.
This book is a 'must read' for cell biologists working in a variety
of fields, from development to wound healing, at all levels -
post-doctoral fellows, post-graduate students and lab technicians.
It is also stimulating reading for molecular and developmental
biologists, biophysicists and biochemists.
particularly fluorescence and live cell imaging, are
revolutionizing the study of cell motility. New bioprobes not only
reveal simple intracellular localization, but also contain details
of post-translational modifications, conformational state and
protein-protein interactions. Coupling these insights with
complementary advances in genetic and biochemical methods is
enabling scientists to understand the processes involved in cell
motility - from molecular motors to cell movements in vivo in a
range of organisms and cell types.
This book features landmark essays that provide an up to date and
fascinating account of current research and concepts in cell
motility.These cover the roles of molecular motors that drive
movement and their interactions with the cytoskeleton as well as
membrane dynamics that allow cells to change shape and to
move.
Cell motility plays a key role in development - there are chapters
on the genetics of cell migration, the regulation of contact
repulsion in growth cones, and the progression from cell migration
to cell-cell adhesion. Cell motility is directional - experts
describe the molecules that regulate chemotaxis, allowing cells to
migrate along pathways specified by chemical gradients. Finally,
cell motility can be perturbed by mutation--metastasis occurs when
cells lose their normal intercellular interactions and invade other
tissue types. All these processes are regulated by signals from the
environment, including other tissues in the body, and the various
molecules that transmit and transduce these signals are
discussed.
This book is a 'must read' for cell biologists working in a variety
of fields, from development to wound healing, at all levels -
post-doctoral fellows, post-graduate students and lab technicians.
It is also stimulating reading for molecular and developmental
biologists, biophysicists and biochemists.
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