Label-Free Technologies For Drug Discovery
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Form:Einzelkauf Download
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Sprache:Englisch
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eBook Format:ePUB
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Produktdetails
Format
ePUB
Kopierschutz
Ja
Family Sharing
Nein
Text-to-Speech
Ja
Erscheinungsdatum
11.02.2011
Herausgeber
Matthew Cooper + weitereVerlag
Wiley-ScrivenerSeitenzahl
352 (Printausgabe)
Dateigröße
4444 KB
Auflage
1. Auflage
Sprache
Englisch
EAN
9781119990277
Over the past two decades the benefits of label-free biosensor
analysis have begun to make an impact in the market, and systems
are beginning to be used as mainstream research tools in many drug
discovery laboratories.
Label-Free Technologies For Drug Discovery summarises the
latest and emerging developments in label-free detection systems,
their underlying technology principles and end-user case studies
that reveal the power and limitations of label-free in all areas of
drug discovery.
Label-free technologies discussed include SPR, NMR,
high-throughput mass spectrometry, resonant waveguide plate-based
screening, transmitted-light imaging, isothermal titration
calorimetry, optical and impedance cell-based assays and other
biophysical methods. The technologies are discussed in relation to
their use as screening technologies, high-content technologies, hit
finding and hit validation strategies, mode of action and ADME/T,
access to difficult target classes, cell-based receptor/ligand
interactions particularly orphan receptors, and antibody and small
molecule affinity and kinetic analysis.
Label-Free Technologies For Drug Discovery is an
essential guide to this emerging class of tools for researchers in
drug discovery and development, particularly high-throughput
screening and compound profiling teams, medicinal chemists,
structural biologists, assay developers, ADME/T specialists, and
others interested in biomolecular interaction analysis.
analysis have begun to make an impact in the market, and systems
are beginning to be used as mainstream research tools in many drug
discovery laboratories.
Label-Free Technologies For Drug Discovery summarises the
latest and emerging developments in label-free detection systems,
their underlying technology principles and end-user case studies
that reveal the power and limitations of label-free in all areas of
drug discovery.
Label-free technologies discussed include SPR, NMR,
high-throughput mass spectrometry, resonant waveguide plate-based
screening, transmitted-light imaging, isothermal titration
calorimetry, optical and impedance cell-based assays and other
biophysical methods. The technologies are discussed in relation to
their use as screening technologies, high-content technologies, hit
finding and hit validation strategies, mode of action and ADME/T,
access to difficult target classes, cell-based receptor/ligand
interactions particularly orphan receptors, and antibody and small
molecule affinity and kinetic analysis.
Label-Free Technologies For Drug Discovery is an
essential guide to this emerging class of tools for researchers in
drug discovery and development, particularly high-throughput
screening and compound profiling teams, medicinal chemists,
structural biologists, assay developers, ADME/T specialists, and
others interested in biomolecular interaction analysis.
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