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Produktbild: Advanced Theranostic Materials

Advanced Theranostic Materials

Aus der Reihe Advanced Materials Series

243,99 €

inkl. gesetzl. MwSt., Versandkostenfrei

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

03.08.2015

Herausgeber

Hirak K. Patra + weitere

Verlag

John Wiley & Sons Inc

Seitenzahl

360

Maße (L/B/H)

23,6/15,7/2,3 cm

Gewicht

612 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-1-118-99829-8

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

03.08.2015

Herausgeber

Verlag

John Wiley & Sons Inc

Seitenzahl

360

Maße (L/B/H)

23,6/15,7/2,3 cm

Gewicht

612 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-1-118-99829-8

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: GPSR Kontakt

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  • Produktbild: Advanced Theranostic Materials
  • Preface xiii
     
    Part 1: System Biology and Translational Medicine
     
    1 Aberrant Signaling Pathways 3
    Gulnaz T. Javan, Sheree J. Finley, Ismail Can, Amandeep Salhotra, Ashinm Malhotra, and Shivani Soni
     
    1.1 Cancer 4
     
    1.2 Pathways Deregulated in Cancer: Introduction 4
     
    1.3 Introduction to Nanotechnology 6
     
    1.3.1 Overview of Clinical Nanotechnology 9
     
    1.3.2 Current Usage in Cancer Treatment 13
     
    1.4 Current Uses in Cancer Diagnostic 14
     
    1.4.1 The Phosphatidylinositol 3-Kinase-AKT Pathway 15
     
    1.4.2 The MAPK Pathway 18
     
    1.4.3 mTOR Pathway 20
     
    1.4.4 Receptor Tyrosine Kinase 23
     
    Acknowledgment 26
     
    References 27
     
    2 Application of Nanoparticles in Cancer Treatment 37
    Behnoud Hormozi
     
    2.1 Introduction 38
     
    2.1.1 Nanotechnology 38
     
    2.1.2 Nanobiotechnology 38
     
    2.1.3 Nanotechnology in Medicine 39
     
    2.1.4 Cancer and Nano in Medicine 41
     
    2.2 Nanoparticles in Cancer Treatment 41
     
    2.3 Nanoparticle Platforms as Drug Delivery Systems for Cancer Therapy 43
     
    2.3.1 Lipid-based Nanoparticle Platforms 44
     
    2.3.2 Polymer-based Nanoparticle Platforms 45
     
    2.3.3 Protein-based Nanoparticle Platforms 47
     
    2.3.4 Inorganic Nanoparticle Platforms 47
     
    2.4 Theranostic Nanomedicine 50
     
    2.4.1 Theranostic Nanomedicine for Cancer Therapy 54
     
    2.5 Selective Drug Delivery and Encapsulation for Chemotherapy 54
     
    2.6 Stimuli-Sensitive Nanopreparations 55
     
    2.7 Multifunctional Nanopreparations 56
     
    2.8 Cancer Nanotechnology: Future and Challenges 58
     
    References 59
     
    3 Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems for Stimuli-Responsive Controlled Release 67
    Xuezhong Du
     
    3.1 Introduction 68
     
    3.2 Protein-Gated MSN Drug Delivery Systems 69
     
    3.2.1 Ligand-Binding Protein-Gated MSN Systems 70
     
    3.2.2 Metal-Chelating Protein-Gated MSN Systems 74
     
    3.3 DNA-Gated MSN Drug Delivery Systems 75
     
    3.3.1 Single-Stranded DNA-Gated MSN Systems 76
     
    3.3.2 Double-Stranded DNA-Gated MSN Systems 77
     
    3.3.3 Hairpin or Quadruplex DNA-Gated MSN Systems 80
     
    3.3.4 Native DNA-Gated MSN Systems 83
     
    3.3.5 Near-Infrared Light-Triggered DNA-Gated MSN Systems 87
     
    3.4 Conclusions and Perspectives 89
     
    Acknowledgments 90
     
    References 90
     
    4 Construction of Functional DNA Nanostructures for Theranostic Applications 93
    Jiang Li, Fan Li, Hao Pei, Lihua Wang, Qing Huang, and Chunhai Fan
     
    4.1 The Progress of Structural DNA Nanotechnology 94
     
    4.2 DNA Nanostructures for Diagnostics 96
     
    4.3 DNA Nanostructures for Diagnostics on the Interface 96
     
    4.4 Diagnostic in Homogeneous Solution 99
     
    4.4.1 Spherical Nucleic Acids (SNA) Probes for Detections in Solution 99
     
    4.4.2 Nanochips in Solution 100
     
    4.4.3 Intracellular/In Vivo Diagnosis 103
     
    4.5 DNA Nanostructures for Therapeutics 106
     
    4.5.1 Delivery of Small-Molecular Drugs 107
     
    4.5.2 Delivery of CpG DNAs 109
     
    4.5.3 RNA Interference (RNAi) 111
     
    4.5.4 Delivery of Proteins 114
     
    4.6 Integration of Diagnosis and Therapy: Smart DNA Theranostic Nanodevices 115
     
    4.7 Targeted Delivery 115
     
    4.8 Controlled/Triggered Release 117
     
    4.9 Summary and Perspectives 119
     
    4.9.1 The Bioeffects of DNA Nanostructures 119
     
    4.9.2 Purity and Yield 120
     
    4.9.3 Dynamic Structures for Theranostic 120
     
    References 121
     
    Part 2: Imaging and Therapeutics
     
    5 Dimercaptosu