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Produktbild: Industrial Microbiology
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Industrial Microbiology

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

15.01.2020

Abbildungen

56

Herausgeber

David B. Wilson + weitere

Verlag

Wiley-VCH

Seitenzahl

424

Maße (L/B/H)

24,6/16,9/2,2 cm

Gewicht

810 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-3-527-34035-4

Beschreibung

Portrait

David Wilson, PhD, was a Professor of Biochemistry, Molecular and Cell Biology at Cornell University in Ithaca (USA).

 

Hermann Sahm, PhD, is Emeritus Professor of Biotechnology at the University of Düsseldorf (Germany).

 

Peter Stahmann, PhD, is Professor for Technical Microbiology at Brandenburg University of Technology Cottbus-Senftenberg in Senftenberg (Germany).

 

Mattheos Koffas, PhD, is Professor of Biology at Rensselaer Polytechnic Institute in Troy (USA).

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

15.01.2020

Abbildungen

56

Herausgeber

Verlag

Wiley-VCH

Seitenzahl

424

Maße (L/B/H)

24,6/16,9/2,2 cm

Gewicht

810 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-3-527-34035-4

Herstelleradresse

Wiley-VCH GmbH
Boschstraße 12
69469 Weinheim
DE

Email: GPSR Kontakt

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  • Produktbild: Industrial Microbiology
  • HISTORICAL OVERVIEW AND FUTURE PERSPECTIVE

    Use of fermentation procedures prior to the discovery of microorganisms (Neolithic Era = New Stone Age until 1850)

    Investigation of microorganisms and beginning of industrial microbiology (1850 until 1940)

    Development of new products and processes: antibiotics and other biomolecules (after 1940)

    Genetic engineering as successful tool for industrial microorganisms (after 1980)

    Future perspectives: Synthetic microbiology

    BIOPROCESS ENGINEERING

    Introduction

    Non-structured models

    Oxygen transport

    Heat generating aerobic processes

    Product recovery

    Modeling and simulation of reactor behavior

    Scale-up

    FOOD

    Fermented foods

    Microorganisms and metabolism

    Yeast fermentations - Industrial application of Saccharomyces species

    Vinegar - Incomplete ethanol oxidation by acetic acid bacteria such as Gluconobacter oxidans

    Bacterial and mixed fermentations- Industrial application of lactic acid bacteria, with or without yeast or molds

    Fungi as food

    Conclusions and outlook

    INDUSTRIAL ALCOHOLS AND KETONES

    Introduction

    Ethanol synthesis by Saccharomyces cerevisiae and Clostridium autoethanogenum

    1,3-Propanediol synthesis by Escherichia coli

    Butanol and isobutanol synthesis by clostridia and yeast

    Acetone synthesis by solventogenic clostridia

    Outlook

    ORGANIC ACIDS

    Introduction

    Citric acid

    Lactic acid

    Gluconic acid

    Succinic acid

    Itaconic acid

    Downstream options for organic acids

    Perspectives

    AMINO ACIDS

    Introduction

    Production of amino acids

    L-Glutamate synthesis by Corynebacterium glutamicum

    L-Lysine

    L-Threonine synthesis by Escherichia coli

    L-Phenylalanine

    Outlook

    VITAMINS, NUCLEOTIDES, CAROTENOIDS

    Application and economic impact

    L-Ascorbic acid (vitamin C)

    Riboflavin (vitamin B2)

    Cobalamin (vitamin B12)

    Purine nucleotides

    ß-Carotene

    Perspectives

    ANTIBIOTICS AND PHARMACOLOGICALLY ACTIVE COMPOUNDS

    Microbial substances active against infectious disease agents or affecting human cells

    beta-Lactams

    Lipopeptides

    Macrolides

    Tetracyclines

    Aminoglycosides

    Claviceps alkaloids

    Perspectives

    PHARMACEUTICAL PROTEINS

    History, main areas of application and economic importance

    Industrial expression systems, cultivation and protein isolation and legal framework

    Insulins

    Somatropin

    Interferons ? Application and manufacturing

    Human granulocyte colony-stimulating factor

    Vaccines

    Antibody fragments

    Enzymes

    Peptides

    View - Future economic importance

    ENZYMES

    Fields of application and economic impacts

    Enzyme discovery and improvement

    Production process for bacterial or fungal enzymes

    Polysaccharide-hydrolyzing enzymes

    Enzymes used as cleaning agents

    Feed supplements - phytases

    Enzymes for chemical and pharmaceutical industry

    Enzymes as highly selective tools for research and diagnostics

    Perspectives

    MICROBIAL POLYSACCHARIDES

    Introduction

    Heteropolysaccharides

    Homopolysaccharides

    Perspectives

    STEROIDS

    Fields of applications and economic importance

    Advantages of biotransformations during production of steroids

    Development of production strains and production processes

    Applied types of biotransformation

    Synthesis of steroids in organic-aqueous biphasic systems

    Side chain degradation at phytosterols by Mycobacterium to gain steroid intermediates

    Biotransformation of cholesterol to gain key steroid intermediates

    11-Hydroxylation by fungi during synthesis of corticosteroids

    delta1-dehydrogenation by Arthrobacter for the production of prednisolone

    17-keto reduction by Saccharomyces in testosterone production

    Double bond isomerization of steroids

    Perspectives

    BIOLEACHING

    Mineral-oxidizing acidophilic bacteria dissolve metals from sulfide ores

    Bioleaching of copper, nickel, zinc and cobalt

    Gold

    Uranium

    Perspectives

    WASTEWATER TREATMENT PROCESSES

    Introduction

    Biological treatments for carbon, nitrogen and phosphorus removal

    Wastewater treatment processes

    Advanced wastewater treatment

    Future perspectives