List of Contributors vii
Foreword xii
Preface xiii
Acknowledgments xiv
Part 1 Factors of High-Risk Pregnancy
1 Overview of High-Risk Pregnancy 1
Catherine Y. Spong and Charles J. Lockwood
2 Nutrition in Pregnancy 2
Cara D. Dolin and Michelle A. Kominiarek
3 Alcohol and Substance Use Disorder 17
Anthony M. Kendle and Sarah G. Obic¿n
4 Environmental Agents and Reproductive Risk 33
Laura Goetzl and Sami Backley
Part 2 Genetics
5 Genetic Screening for Mendelian Disorders 44
Deborah A. Driscoll and Lorraine Dugoff
6 Screening for Congenital Heart Disease 50
Lynn L. Simpson
7 First- and Second-Trimester Screening for Fetal Aneuploidy and Neural Tube Defects 60
Ronan Daly and Fergal D. Malone
Part 3 Fetal Assessment
8 Sonographic Dating and Standard Fetal Biometry 70
Anna Hayes Nutter and Alfred Abuhamad
9 Antepartum Fetal Monitoring 83
Michael Nageotte
10 Interpreting Intrapartum Fetal Heart Tracings 88
Lorie M. Harper and Alison G. Cahill
Part 4 Maternal Disease
11 Sickle Cell Anemia 93
Scott Roberts
12 Anemia 99
Elaine L. Duryea and Rachel C. Schell
13 Thrombocytopenia 105
Ann M. Bruno and Robert M. Silver
14 Inherited and Acquired Thrombophilias 114
Pouya Abhari and Michael J. Paidas
15 Thromboembolic Disorders 123
Audrey A. Merriam and Christian M. Pettker
16 Cardiac Disease in Pregnancy 134
Sarah Rae Easter
17 Renal Disease 142
Shivani Patel
18 Pregnancy in Transplant Patients 148
Lisa A. Coscia Serban Constantinescu and Michael J. Moritz
19 Gestational Diabetes Mellitus 156
Angela R. Boyd and Deborah L. Conway
20 Diabetes Mellitus 161
George R. Saade
21 Thyroid Disorders 165
Elizabeth O. Buschur and Stephen F. Thung
22 Asthma 170
Jennifer Namazy and Michael Schatz
23 Epilepsy 182
Regan J. Lemley and P. Emanuela Voinescu
24 Chronic Hypertension 191
Christina L. Herrera
25 Systemic Lupus Erythematosus 197
Michael Richley and Christina S. Han
26 Perinatal Infections 206
Michelle E. Whittum and Stephanie T. Ros
27 Malaria 218
Richard M.K. Adanu
28 Hepatitis in Pregnancy 221
Asa Oxner Andrew Myers and Sarah G. Obic¿n
29 HIV Infection 229
Emily H. Adhikari
30 Pregnancy in Women with Disabilities 237
Caroline Signore
31 COVID-19 in Pregnancy 253
Carolynn M. Dude, Martina L. Badell and Denise J. Jamieson
Part 5 Obstetric Complications
32 Recurrent Pregnancy Loss 262
Claudio V. Schenone and Stephanie T. Ros
33 Cervical Insufficiency 272
Rachel Sinkey and John Owen
34 Gestational Hypertension, Preeclampsia, and Eclampsia 281
Michal Fishel Bartal and Baha M. Sibai
35 Postpartum Hemorrhage 288
David B. Nelson
36 Emergency Care 300
Sarah Rae Easter
37 Rh and Other Blood Group Alloimmunizations 312
Kenneth J. Moise Jr.
38 Multiple Gestations 319
Maria Andrikopoulou and Mary E. D'Alton
39 Polyhydramnios and Oligohydramnios 332
Ron Beloosesky and Michael G. Ross
40 Pathogenesis and Prediction of Preterm Delivery 344
Anthony M. Kendle, Catalin S. Buhimschi, and Charles J. Lockwood
41 Preterm (Prelabor) Premature Rupture of Membranes 361
Brian M. Mercer and Kelly S. Gibson
42 Management of Preterm Labor 372
Georgios Doulaveris and Vincenzo Berghella
43 Placenta Previa and Related Disorders 381
Yinka Oyelese
44 Fetal Growth Restriction 392
Katherine H. Bligard and Anthony O. Odibo
Part 6 Complications of Labor and Delivery
45 Induction of Labor 399
Emily H. Adhikari
46 Cesarean Delivery 406
Elaine L. Duryea
47 Vaginal Birth after Cesarean Delivery 415
Mark B. Landon
48 Breech Delivery 425
G.J. Hofmeyr and M.N. Nassali
49 Operative Vaginal Delivery 432
Edward R. Yeomans and Ann Erickstad
50 Obstetric Analgesia and Anesthesia 437
Gilbert J. Grant
51 Quality and Patient Safety 443
Christian M. Pettker
Part 7 Procedures
52 Genetic Amniocentesis, Chorionic Villus Sampling, Intrauterine Transfusion, and Shunts 450
Ann McHugh and Russell S. Miller
53 Fetal Surgery 465
Marisa Eve Schwab and Hanmin Lee
Index 474
