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Produktbild: FOXO Transcription Factors
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FOXO Transcription Factors Methods and Protocols

Aus der Reihe Methods in Molecular Biology
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101,99 € UVP 117,69 €

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

10.12.2019

Abbildungen

XII, 270 p. 54 illus., 33 illus. in color.

Herausgeber

Wolfgang Link

Verlag

Springer Us

Seitenzahl

270

Maße (L/B/H)

25,4/17,8/1,6 cm

Gewicht

540 g

Auflage

Softcover reprint of the original 1st ed. 2019

Sprache

Englisch

ISBN

978-1-4939-9409-0

Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

10.12.2019

Abbildungen

XII, 270 p. 54 illus., 33 illus. in color.

Herausgeber

Wolfgang Link

Verlag

Springer Us

Seitenzahl

270

Maße (L/B/H)

25,4/17,8/1,6 cm

Gewicht

540 g

Auflage

Softcover reprint of the original 1st ed. 2019

Sprache

Englisch

ISBN

978-1-4939-9409-0

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: FOXO Transcription Factors

  • Introduction to FOXO Biology.- Characterization of microRNAs Regulating FOXO Expression.- Identification of Transcription Factor Binding Sites in the Mouse FoxO1 Promoter.- Investigating Mechanisms that control Ubiquitin-mediated DAF-16/FOXO Protein Turnover.- Phosphorylation of FOXO Proteins as a Key Mechanism to Regulate their Activity.- Methodological Approach for the Evaluation of FOXO as a Positive Regulator of Antioxidant Genes.- Characterization of FOXO Acetylation.- Transcriptional Activity of FoxO Transcription Factors Measured by Luciferase Assays.- Monitoring the Transcriptional Activity of FOXO Transcription Factors by Analyzing their Target Genes.- Using ChIP-based Approaches to Characterize FOXO Recruitment to its Target Promoters.- RNAi Mediated Silencing of FoxO Factors.- Immunofluorescence Analysis by Confocal Microscopy for Detecting Endogenous FOXO.- High Throughput Image-based Screening to Identify Chemical Compounds Capable of Activating FOXO.- Image-based Identification of Chemical Compounds Capable of   Trapping FOXO in the Cell Nucleus.- Quantifying Tissue-specific Overexpression of
    FOXO
    in
    Drosophila
    via mRNA Fluorescence
    in situ
    Hybridization using Branched DNA Probe Technology.- Genome-wide Analysis for Identifying FOXO Protein Binding Sites.- Mathematical Modeling of Nuclear Trafficking of  FOXO Transcription Factors.- Following Transcriptome to Uncover FOXO Biological Functions.- Hydra as Model to Determine the Role of FoxO in Longevity.- Genetic Ablation of FOXO in Mice to Investigate its Physiological Role.- Analysis of
    FOXO3
    Gene Polymorphisms Associated with Human Longevity.- Analysis of
    FOXO3a
    Gene Polymorphism Associated with Asthma.