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Produktbild: The Design and Development of Novel Drugs and Vaccines

The Design and Development of Novel Drugs and Vaccines Principles and Protocols

135,99 €

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

22.01.2021

Abbildungen

60 illustrations (30 in full color), Illustrationen, nicht spezifiziert

Herausgeber

Tarun Kumar Bhatt + weitere

Verlag

Elsevier Science & Technology

Seitenzahl

308

Maße (L/B/H)

22,6/15,2/1,8 cm

Gewicht

658 g

Sprache

Englisch

ISBN

978-0-12-821471-8

Beschreibung

Rezension

"I have read other books on clinical research, but none with the level of detail and particular focus on drug design (the computational drug design sections) that this one has. This book is very detailed-oriented from that standpoint, and it can certainly serve as a useful tool for those developing vaccines." --© Doody's Review Service, 2021, Patrick J Scoble, PharmD(PJS Pharma Consulting LLC), reviewer, expert opinion

Portrait

Tarun Kumar Bhatt is an Assistant Professor in the Department of Biotechnology, at the Central University of Rajasthan, India. He received his PhD from the International Centre for Genetic Engineering and Biotechnology, New Delhi and gained post-doctoral experience at the Scripps Research Institute in San Diego, California. He has published over 25 articles and has extensive experience researching drug and vaccine development.

Surendra Nimesh, UGC Assistant Professor at Central University of Rajasthan, Rajasthan, India. Surendra received his M.S. in Biomedical Science from the Dr. B.R. Ambedkar Center for Biomedical Research (ACBR), University of Delhi. He completed his PhD. In Nanotechnology at the Institute of Genomics and Integrative Biology (CSIR), Delhi. After completing his postdoctoral studies at the Ecole Polyetchnique of Montreal, Surendra joined the Clinical Research Institute of Montreal (IRCM), Canada as Postdoctoral Fellow. After completing his commitment at IRCM, he joined McGill University for short time. He also worked as NSERC visiting fellow at Health Canada, Canada. His research interests include nanoparticles-mediated gene, siRNA and drug delivery.

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

22.01.2021

Abbildungen

60 illustrations (30 in full color), Illustrationen, nicht spezifiziert

Herausgeber

Verlag

Elsevier Science & Technology

Seitenzahl

308

Maße (L/B/H)

22,6/15,2/1,8 cm

Gewicht

658 g

Sprache

Englisch

ISBN

978-0-12-821471-8

EU-Ansprechpartner

Zeitfracht Medien GmbH
Ferdinand-Jühlke-Straße 7|99095|Erfurt|DE
produktsicherheit@zeitfracht.de

Herstelleradresse

Elsevier Science & Technology
125 London Wall|EC2Y 5AS|London|GB
tradeorders@elsevier.com

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  • Produktbild: The Design and Development of Novel Drugs and Vaccines

  • 1. Introduction of structural bioinformatics with respect to drug discovery
    2. Target identification and validation
    3. Retrieval of compounds
    4. Lead identification and optimization
    5. Molecular dynamics simulations
    6. An overview of vaccine design
    7. Key steps in the selection of vaccine targets
    8. Epitope prediction and selection of linkers and adjuvant
    9. Design of vaccine constructs
    10. In-silico validation through protein-protein docking
    11. Molecular cloning
    12. Protein expression
    13. Protein purification and desalting
    14. Biological assay
    15. Biophysical methods
    16. Outline of animal study for lead/ vaccine testing
    17. Evaluation of immunogenicity of vaccine candidate
    18. In-vitro evaluation of lead molecule
    19. Medical physiological parameter for lead/vaccine testing
    20. Brief introduction of clinical research and trials
    21. An overview of IND, NDA, approval agencies and FDA post-marketing surveillance
    22. Introduction of Intellectual property rights